2019-06-06 12:19:552025-04-07 09:19:24
locus
BSU01740
BSU_01740
outlinks
bsu
BSU01740
BSU_01740
The protein
Protein family
anti-sigma-W factor family (according to Swiss-Prot)
zinc-associated anti-sigma factor (ZAS) superfamily (with [[protein|YlaD]], according to UniProt)
anti-sigma-W factor family (single member, according to UniProt)
The protein
[SW|Localization]
membrane (according to Swiss-Prot)
cell membrane (according to UniProt)
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
The cytoplasmic domain is able to inactivate SigW and the extracellular and transmembrane domains are crucial for sensing and transducing the signal that triggers SigW activation (PubMed:15130127). The N-terminus binds the zinc ion and is followed by a long helix (about residues 40-80) that fits into a hydrophobic surface groove on SigW, probably blocking its ability to interact with the -10 and -35 promoter elements (PubMed:28319136).